Akihide Tanimoto Selected Research

Histamine Receptors (Histamine Receptor)

12/2016	Critical in vivo roles of histamine and histamine receptor signaling in animal models of metabolic syndrome.
7/2016	Novel function of histamine signaling via histamine receptors in cholesterol and bile acid metabolism: Histamine H2 receptor protects against nonalcoholic fatty liver disease.
2/2015	Novel function of histamine signaling in hyperlipidemia-induced atherosclerosis: Histamine H1 receptors protect and H2 receptors accelerate atherosclerosis.
9/2013	Histamine receptors expressed in circulating progenitor cells have reciprocal actions in ligation-induced arteriosclerosis.
4/2011	Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level.
8/2010	Histamine regulation in glucose and lipid metabolism via histamine receptors: model for nonalcoholic steatohepatitis in mice.
3/2010	[Role of histamine in atherosclerotic lesions].
2/2005	Granulocyte macrophage-colony stimulating factor increases the expression of histamine and histamine receptors in monocytes/macrophages in relation to arteriosclerosis.

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Akihide Tanimoto Research Topics

Disease

37	Neoplasms (Cancer) 05/2022 - 01/2002
27	Atherosclerosis 07/2021 - 01/2004
10	Breast Neoplasms (Breast Cancer) 12/2021 - 03/2011
9	Carcinoma (Carcinomatosis) 12/2021 - 01/2003
8	Neoplasm Metastasis (Metastasis) 04/2022 - 06/2014
7	Non-alcoholic Fatty Liver Disease 08/2021 - 08/2010
7	Inflammation (Inflammations) 07/2020 - 03/2010
7	Hyperlipidemias (Hyperlipidemia) 02/2015 - 08/2010
6	Hypercholesterolemia 01/2016 - 09/2010
5	Lymphatic Metastasis 04/2022 - 03/2011
5	Adenocarcinoma 10/2021 - 07/2016
5	Atherosclerotic Plaque (Atheroma) 12/2016 - 05/2005
5	Arteriosclerosis 01/2015 - 02/2005
4	Infections 01/2021 - 07/2015
4	Hypertension (High Blood Pressure) 11/2017 - 12/2014
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017 - 12/2013
4	Myocardial Infarction 01/2017 - 04/2008
4	Vascular System Injuries 02/2013 - 05/2005
3	Stomach Neoplasms (Stomach Cancer) 04/2022 - 01/2020
3	Endometrial Neoplasms (Endometrial Cancer) 02/2022 - 11/2020
3	Hepatocellular Carcinoma (Hepatoma) 09/2021 - 01/2002
3	Wounds and Injuries (Trauma) 05/2020 - 11/2017
3	Carcinogenesis 01/2020 - 07/2016
3	Short Bowel Syndrome 12/2018 - 05/2013
3	Insulin Resistance 01/2017 - 08/2010
3	Body Weight (Weight, Body) 01/2017 - 09/2010
3	Fibrosis (Cirrhosis) 03/2014 - 09/2002
3	Neointima 05/2008 - 05/2005
2	Glioblastoma (Glioblastoma Multiforme) 06/2022 - 01/2022
2	Lung Neoplasms (Lung Cancer) 01/2022 - 03/2017
2	Microsatellite Instability 09/2021 - 11/2020
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020 - 07/2016
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 12/2019 - 01/2017
2	Sarcoma (Soft Tissue Sarcoma) 12/2019 - 07/2011
2	Liver Diseases (Liver Disease) 12/2018 - 12/2016
2	Intestinal Failure 12/2018 - 12/2016
2	Vascular Remodeling 05/2017 - 12/2002
2	Esophageal Squamous Cell Carcinoma 01/2017 - 08/2003
2	Osteosarcoma (Osteogenic Sarcoma) 01/2016 - 06/2014
2	Cardiomegaly (Heart Hypertrophy) 01/2015 - 01/2014
2	Hyperglycemia 12/2014 - 11/2010
2	Triple Negative Breast Neoplasms 10/2011 - 04/2011
2	Ductal Carcinoma 04/2011 - 03/2011

Drug/Important Bio-Agent (IBA)

19	CholesterolIBA 08/2021 - 05/2005
15	Histamine (Histamine Dihydrochloride)FDA Link 12/2016 - 01/2004
9	Proteins (Proteins, Gene)FDA Link 12/2021 - 12/2010
8	LipidsIBA 08/2021 - 09/2010
8	Histamine Receptors (Histamine Receptor)IBA 12/2016 - 02/2005
7	MucinsIBA 12/2020 - 04/2011
6	ParaffinIBA 09/2021 - 03/2011
6	Matrix Metalloproteinases (MMPs)IBA 07/2020 - 01/2004
6	ApolipoproteinsIBA 02/2015 - 05/2005
6	Histidine DecarboxylaseIBA 04/2011 - 01/2003
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2008
5	Nitric Oxide Synthase (NO Synthase)IBA 11/2021 - 07/2005
5	DNA (Deoxyribonucleic Acid)IBA 09/2021 - 03/2017
4	PeroxiredoxinsIBA 01/2019 - 11/2012
4	AntigensIBA 02/2018 - 07/2003
4	AntibodiesIBA 06/2017 - 01/2007
4	MAP Kinase Kinase Kinase 5IBA 05/2017 - 07/2011
4	Apolipoproteins E (ApoE)IBA 02/2015 - 04/2011
4	LDL CholesterolIBA 01/2011 - 09/2010
4	EnzymesIBA 08/2010 - 06/2004
3	VimentinIBA 05/2022 - 07/2003
3	Peptides (Polypeptides)IBA 12/2021 - 08/2014
3	Protein Isoforms (Isoforms)IBA 11/2021 - 07/2005
3	Cholic AcidIBA 08/2021 - 01/2014
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 11/2012
3	Glucose (Dextrose)FDA LinkGeneric 12/2013 - 08/2010
3	HDL CholesterolIBA 01/2011 - 09/2010
3	Cholesterol Esters (Cholesteryl Esters)IBA 01/2011 - 09/2010
3	oxidized low density lipoproteinIBA 01/2011 - 09/2010
2	ErbB Receptors (EGF Receptor)IBA 06/2022 - 04/2022
2	DesminIBA 05/2022 - 01/2007
2	Nucleic AcidsIBA 01/2022 - 12/2018
2	Epidermal Growth Factor (EGF)IBA 12/2021 - 08/2003
2	Calmodulin (Calcium-Dependent Activator Protein)IBA 12/2021 - 08/2014
2	human ERBB2 proteinIBA 12/2021 - 01/2020
2	Formaldehyde (Formol)FDA Link 09/2021 - 11/2020
2	Pharmaceutical PreparationsIBA 01/2021 - 12/2010
2	Messenger RNA (mRNA)IBA 12/2018 - 03/2017
2	SERPIN-B5 (maspin)IBA 12/2018 - 04/2011
2	Bile Acids and Salts (Bile Acids)IBA 08/2018 - 07/2016
2	CollagenIBA 11/2017 - 11/2012
2	S100 Proteins (S 100 Protein)IBA 01/2017 - 08/2010
2	AdiponectinIBA 01/2017 - 12/2013
2	GhrelinIBA 12/2016 - 12/2016
2	Histamine H1 Receptors (Histamine H1 Receptor)IBA 12/2016 - 02/2015
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2014 - 11/2010
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2014 - 09/2002
2	Streptozocin (Streptozotocin)FDA Link 12/2013 - 11/2010
2	Aldehyde Dehydrogenase 1 FamilyIBA 10/2011 - 03/2011
2	Histidine (L-Histidine)FDA Link 03/2010 - 06/2004

Therapy/Procedure

9	Therapeutics 01/2022 - 01/2004
6	Drug Therapy (Chemotherapy) 04/2022 - 06/2014
6	Ligation 05/2017 - 12/2002
3	Radiotherapy 08/2020 - 11/2018
2	Lymph Node Excision (Lymph Node Dissection) 04/2022 - 08/2020
2	Total Parenteral Nutrition 12/2018 - 12/2016
2	Parenteral Nutrition 12/2016 - 12/2016